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I have just been on Aromasin just 9 days and so far have no side effects. I tried Femara and after 14 days went off it because of joint pain and fatigue. On Femara it was so bad that I couldn't climb my staircase without crying. So far Aromasin is a miracle drug for me if it stops estrogen in its tracks!
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Similar results were observed for total hip BMD.
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However, arthralgia was an AE common to both exemestane and tamoxifen.
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Local application of estrogen in the rat hippocampus has been shown to inhibit the re-uptake of serotonin.
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In the trial, women were given either Afinitor and another breast cancer drug, exemestane, or exemestane and a placebo.
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The guideline includes the recommendation that women with stage I to III disease consider taking tamoxifen for 10 years.
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Approximately 33% of patients, and nearly 50% of patients in this group are not surgical candidates because of inaccessibility of the tumor, extensive systemic disease, and other factors.
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MRIs are less likely to be helpful for older women with early tumors in one breast and clear mammography readings in the other.
Also added that pCR in patients who received paclitaxel plus trastuzumab 46%, and pCR in patients who received paclitaxel plus trastuzumab plus lapatinib was 56%, indicating no benefit for the addition of lapatinib.
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Removing the ovaries doesn't reduce the risk of breast cancer in postmenopausal women because fat and muscle tissue are the main producers of estrogen in these women.
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