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An earlier short-term double-blind study in patients with acute exacerbations of schizophrenia showed that amisulpride was as effective as risperidone in treating positive symptoms and showed a trend toward greater improvement in negative symptoms; moreover, amisulpride was associated with significantly less weight gain than risperidone ().

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Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies, 2007, Support Care Cancer, 15, pp.

However, because of the adverse adverse-effect profile of clozapine and the significant metabolic risks associated with olanzapine, PORT advised that neither drug should be considered as a first-line treatment for first-episode schizophrenia.

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Clozapine is an atypical antipsychotic medication recommended for Treatment resistant schizophrenia where the illness has not responded satisfactorily to treatment despite sequential use of adequate doses of, at least, two different antipsychotics, prescribed for adequate duration.

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Depending on how each individual is affected by the medications, it may be necessary for the doctor to prescribe more than one consecutively until the proper medication is found that meets the required results.

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Clinicians need to be aware that concomitant treatment with other drugs that cause leucopenia may also increase the risk of agranulocytosis.

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Usually, the diagnosis is confirmed if the psychosis ends after withdrawal from drugs or alcohol, and returns if the patient returns to alcohol or substance abuse.

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In the 1970s, tens of thousands of patients were put on antipsychotic drugs and released from institutions into the community, a concept called deinstitutionalization.

The Medline database was searched for all studies of amisulpride in schizophrenia which reported functional and quality of life outcomes up until 30 September 2009.

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Psychosocial factors are now thought to influence the expression or severity of schizophrenia rather than cause it directly.

Many researchers question the first-line prescribing of atypicals over typicals, and some even question the distinction between the two classes.

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Some psychiatrists are reluctant to take on this responsibility in view of the risks of neutropenia and agranulocytosis and the paucity of evidence available.

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Some reports have suggested that too much use of late in pregnancy may cause a decrease in the newborn's weight and possible death of the fetus or newborn infant.

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However, the significant association observed in cannabidiol-treated patients between improvement of clinical symptoms and serum anandamide levels suggests that the ability of cannabidiol to inhibit the FAAH activity and enhance intrinsic anandamide signaling might be a functionally relevant component of its antipsychotic properties.

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This may be a result of previous conventional antipsychotic treatment, in that nicotine may ameliorate some of the adverse effects of these drugs.

Polymorphisms of the 5-HT 2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in caucasian subjects with a first-episode psychosis.

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The impact of cannabis use on cognitive functioning in patients with schizophrenia: a meta-analysis of existing findings and new data in a first-episode sample.

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Some modifications are done in each patient after looking into all of the factors that take place.

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My advise would be to either quit drinking totally and ask your doctor to switch you from diazepam to some other med that will actually help you.

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Hyoscyamus Niger this homeopathic remedy is useful for those cases of Schizophrenia where the main symptom is delusion of persecution and the patient feels that others are making some plot against him.

In total, the study examined 39 patients, dosing 20 with CBD and 19 with amisulpride.

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Amisulpride was associated with fewer extrapyramidal adverse effects and fewer drop-outs because of adverse events than conventional drugs.

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

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The effect on prolactin levels of the classical antypsichotic chlorpromazine, used in clinical practice for its anti-nausea properties, has been discussed above.

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Hirsch SR, Kissling W, Bauml J, Power A, O'Connor R (2002) A 28-week comparison of ziprasidone and haloperidol in outpatients with stable schizophrenia.

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Even though the most frequently used antipsychotic was aripiprazole, the study showed that the main reason psychiatrists did not choose aripiprazole was because of its higher price leading to insurance audit.

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The investigators plan to test carefully the possible benefits and problems when the antipsychotic amisulpride or a dummy tablet ('placebo') is added to clozapine for 12 weeks in people whose schizophrenia illness has not been helped much by any antipsychotic medication on its own, and who are now taking clozapine, but again with not much improvement.

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