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This gives galantamine a major advantage in combating the impairments caused by a decline in cholinergic function.

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Therefore, merely observing what does or does not occur during sleep (there are simple devices for detecting this) is sufficient to make the distinction.

Its effects on AChE, BChE, MAO and other key enzymes have been reported.

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Some docking studies performed with Torpedo californica AChE and Buxus alkaloids demonstrated that, as observed for the steroidal alkaloids, the C-3 and C-20 amino groups are essential for the activity, and that the hydrophobicity of the compounds is also related to the inhibitory capacity of the ligands.

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Cholinesterase inhibitors with potential or established clinical effects can be classified as follows: (1) Reversible inhibitors: donepezil, galantamine.

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Later, though, the commercial production of Galantamine was undertaken in Bulgaria.

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