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Levodopa enters the brain and is converted to dopamine while carbidopa prevents or lessens many of the side effects of levodopa, such as nausea, vomiting, and occasional heart rhythm disturbances.

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These findings are balanced by two other findings: those patients treated with levodopa alone had slightly better control of movement and other side effects were more common in the dopamine agonist group than the levodopa groups.

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Now a study by Paolo Barone, MD, PhD, and his colleagues from the University of Naples in Italy reveals that the drug might also reduce the symptoms of depression in people with PD who are depressed.

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