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New data suggesting that combined therapy with T 3 and T 4 could be indicated in some patients with hypothyroidism are assessed, and the indications for TSH suppression with l-T 4 in patients with euthyroid multinodular goiter and in those with differentiated thyroid cancer are reviewed.
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Incident cerebrovascular disease events were unchanged, and incident AF was not related to l-T 4 exposure ().
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